Regulation of acetylcholinesterase expression in the K-562 cell line.
نویسندگان
چکیده
Acetylcholinesterase, an erythroid marker constitutively expressed in K-562 cells, can be further induced by sodium butyrate. The highest level of acetylcholinesterase induction is reached in approximately equal to 3 days, in parallel with increased hemoglobin expression. Acetylcholinesterase induction is reversible, and repeated addition of butyrate is necessary to maintain a high level of the enzyme. Actinomycin D inhibits the induction.
منابع مشابه
Regulation of Acetylcholinesterase Expression in the K-562 Cell Line1
Acetylcholinesterase, an erythroid marker constitutively ex pressed in K-562 cells, can be further induced by sodium butyrate. The highest level of acetylcholinesterase induction is reached in =3 days, in parallel with increased hemoglobin expres sion. Acetylcholinesterase induction is reversible, and repeated addition of butyrate is necessary to maintain a high level of the enzyme. Actinomycin...
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ورودعنوان ژورنال:
- Cancer research
دوره 44 9 شماره
صفحات -
تاریخ انتشار 1984